I'll go ahead and get this thread started with a couple of the most obvious Transhumanist jokes that come to mind.
"How many Transhumanists does it take to change a lightbulb?" "None. Soon our technologically enhanced eyes will have the ability to see in the dark."
"Why didn't the Transhumanist cross the road?" "Because a cryonics contract doesn't help you if a truck makes your brain go splat."
I know, those jokes were kinda lame, but that's all I could think of for now.
See also the
Singularity Humour page on the Transhumanist Wiki, and the videos tagged "
Humor" on this site.